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Tapentadol is an opioid analgesic prescribed for the treatment of moderate to severe pain. Tapentadol works by changing the way the nervous system and brain respond to pain.

General Information

It is available in immediate-release and extended-release oral tablets. Long-acting tapentadol may also be indicated for the treatment of severe neuropathic pain associated with diabetic peripheral neuropathy. Tapentadol may be prescribed when alternative pain treatments do not provide relief. Tapentadol immediate-release tablets are used to treat acute pain. Tapentadol extended-release tablets are prescribed for chronic pain relief for up to 24 hours and should not be taken as needed for pain. Tapentadol works best when taken at the onset of pain; This may not work if the pain level is already high. Tapentadol should only be taken as directed.

Indications and Usage

Tapentadol SR is a planned (controlled) S8 drug indicated for the treatment of moderate to severe chronic pain responsive to non-opioid analgesics. Tapentadol retard may be another option for people with severe and chronic disabling pain for whom non-opioid analgesics do not provide adequate pain relief and for whom opioid trials are indicated as an alternative. Addiction, Abuse, and Abuse: Tapentadol oral or prolonged-release tablets put users at risk for addiction, abuse, and abuse, which can lead to overdose. Assess the risk to the patient before prescribing and regularly monitoring these behaviours and conditions.

To ensure that the benefits of opioid pain relievers outweigh the risks of addiction, abuse, and abuse, the Food and Drug Administration (FDA) required a risk assessment and risk reduction strategy for these products. Life-threatening respiratory depression: Respiratory depression can be severe, life-threatening, or fatal. Monitor carefully, especially at the beginning or after increasing the dose. Accidental ingestion: Accidental ingestion of tapentadol oral or prolonged-release tablets, particularly in children, can result in a fatal tapentadol overdose. Neonatal opiate withdrawal syndrome can be life-threatening if not recognized and treated. If a pregnant woman needs to take long-term opioids, educate the patient about the risk of neonatal opioid withdrawal syndrome and ensure appropriate treatment is available.